How dosage regimes are designed?

The dosage regimen is the frequency at which the drug doses are given to maintain a steady-state serum concentration. Dosage Regimen means dose of drug and dosing interval. Simply, the schedule of doses of a therapeutic agent per unit of time [2]. Dosage regimen is meant the systematized dosage schedule [3].

When we were reading we ran into the question “What is dose regimen design in pharmacology?”.

One way to think about this is iNTRODUCTION Dosage regimen design is the selection of drug dosage, route, and frequency of admin- istration in an informed manner to achieve therapeutic objectives. Deliberate planning of drug therapy is necessary because the administration of drugs usually involves risk of untoward effects.

What is the difference between a therapeutic objective and dosage regimen?

The objective of drug therapy is to bring plasma concentration within the therapeutic window. The dosage regimen is the modality of drug administration that is chosen to reach the therapeutic objective. This depends on the drug used, the condition to be treated, and the patient’s characteristics.

What is the meaning of dosage in medical terms?

According to the AMA (American Medical Association) Manual of Style, Dosage is the prescribed administration of a predetermined amount, number, and frequency of doses of drug over a specific period of time . Example of dosage: 200 mg lesinurad once daily .

What is the maintenance dose of a drug?

Such dose is known as maintenance dose., and  i., and e. Maintain the response of drug by replacing drug lost during dosing interval.  Maintenance dose = loading dose x ( 1- e -k‫ז‬ )  Loading dose = maintenance dosemaintenance dose 1 – e1 – e -K-K ‫ז‬‫ז‬.

In addition, the dose of a drug is governed by its inherent potency. For example, the analgesic dose of Aspirin for headache is 300-600mg, the antiplatelet dose is 60-150mg/day, and the anti-inflammatory dose for rheumatoid arthritis is 3-5g/day. Generally, drug doses are expressed as microgram (µg), milligram (mg), and milliliter.

What is dose regimen?

For webmasters: dosage regimen. The schedule of doses of a therapeutic agent per unit of time, including: the time between doses (e. g, every 6 hours) or the time when the dose(s) are to be given (e. g, at 8 a. m. and 4 p. m. daily), and the amount of a medicine (e. g, number of capsules) to be given at each specific time.

Dosage regimen is defined as the manner in which a drug is taken. For some drugs like analgesics, hypnotics, antiemetics, etc, a single dose may provide effective treatment. However, the duration of most illnesses is longer than the therapeutic effect produced by a single dose.